Products for Research Use Only
RegisterLogin

CRBN ligand-690

CAT: 0804-HY-W953512Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W953512Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-690 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-690 can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2925093-74-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=CC1=CC=C(C=2C=CN(C12)C)N3C(=O)NC(=O)CC3
Molecular Formula
C14H13N3O3
Molecular Weight
271.28
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Chemical Information

4-(2,4-dioxo-1,3-diazinan-1-yl)-1-methyl-1H-indole-7-carbaldehyde
CAS Number2925093-74-7
PubChem CID169548614
IUPAC Name4-(2,4-dioxo-1,3-diazinan-1-yl)-1-methylindole-7-carbaldehyde
Molecular FormulaC14H13N3O3
Molecular Weight271.27
XLogP0.1
Topological Polar Surface Area71.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity439
SMILES
CN1C=CC2=C(C=CC(=C21)C=O)N3CCC(=O)NC3=O
InChI
InChI=1S/C14H13N3O3/c1-16-6-4-10-11(3-2-9(8-18)13(10)16)17-7-5-12(19)15-14(17)20/h2-4,6,8H,5,7H2,1H3,(H,15,19,20)
InChIKey
GHRYHRWIKYKHAM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(2,4-dioxo-1,3-diazinan-1-yl)-1-methyl-1H-indole-7-carbaldehyde
CAS: 2925093-74-7
CID: 169548614
Formula: C14H13N3O3
MW: 271.27
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight271.27
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass271.09569129
Monoisotopic Mass271.09569129
Topological Polar Surface Area71.4 Ų
Heavy Atom Count20
Formal Charge0
Complexity439
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-179733CRBN ligand-191
HY-169989-01CRBN ligand-11
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W999738CRBN ligand-834
HY-W999733CRBN ligand-832
HY-W999729CRBN ligand-851
HY-W999717CRBN ligand-282

Alternative Products

CatalogName
GTR19276728-01CRBN ligand-690
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
T205577-01CRBN ligand-45
T205145-01CRBN ligand-47
T9360-01CRBN ligand-9
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164

Popular Products