Products for Research Use Only
RegisterLogin

CRBN ligand-581

CAT: 0804-HY-W953224Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W953224Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-581 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-581 can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2925085-87-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(=O)CCN1C=2C=C(N)C3=C(C=NN3C)C2
Molecular Formula
C12H13N5O2
Molecular Weight
259.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Chemical Information

1-(7-amino-1-methyl-1H-indazol-5-yl)-1,3-diazinane-2,4-dione
CAS Number2925085-87-4
PubChem CID169548541
IUPAC Name1-(7-amino-1-methylindazol-5-yl)-1,3-diazinane-2,4-dione
Molecular FormulaC12H13N5O2
Molecular Weight259.26
XLogP-0.4
Topological Polar Surface Area93.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity402
SMILES
CN1C2=C(C=C(C=C2N)N3CCC(=O)NC3=O)C=N1
InChI
InChI=1S/C12H13N5O2/c1-16-11-7(6-14-16)4-8(5-9(11)13)17-3-2-10(18)15-12(17)19/h4-6H,2-3,13H2,1H3,(H,15,18,19)
InChIKey
SQPFCPVWPJDCIL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(7-amino-1-methyl-1H-indazol-5-yl)-1,3-diazinane-2,4-dione
CAS: 2925085-87-4
CID: 169548541
Formula: C12H13N5O2
MW: 259.26
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight259.26
XLogP3-0.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass259.10692467
Monoisotopic Mass259.10692467
Topological Polar Surface Area93.3 Ų
Heavy Atom Count19
Formal Charge0
Complexity402
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-179733CRBN ligand-191
HY-169989-01CRBN ligand-11
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W999738CRBN ligand-834
HY-W999733CRBN ligand-832
HY-W999729CRBN ligand-851
HY-W999717CRBN ligand-282

Alternative Products

CatalogName
GTR19275880-01CRBN ligand-581
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
T205577-01CRBN ligand-45
T205145-01CRBN ligand-47
T9360-01CRBN ligand-9
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164

Popular Products