GR125487

CAT: 0804-HY-W822786Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-W822786Size:1 Each

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Description

GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3 receptors (Kd > 1 μM) . GR125487 completely antagonizes the memory-promoting effect of BIMU1, and its administration alone has no significant effect on basic social memory. GR125487 can be used for the study of social olfactory memory[1].

CAS Number

144625-67-2

UNSPSC

12352005

Target

5-HT Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(OCC1CCN(CCNS(=O)(=O)C)CC1)C2=C(OC)NC=3C=CC(F)=CC32

Molecular Formula

C19H26FN3O5S

Molecular Weight

427.49

References & Citations

[1]Letty S, et al. 5-HT4 receptors improve social olfactory memory in the rat. Neuropharmacology. 1997 Apr-May;36 (4-5) :681-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT4 Receptor

GR125487

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