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Lactate (sodium) -13C2

CAT: 0804-HY-W769991Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W769991Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lactic acid-13C2 (DL-Lactic acid-13C2) sodium is the 13C-labeled Lactic acid sodium . Lactic acid (DL-Lactic acid) sodium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity[1][2]. Lactic acid sodium also has antimicrobial activity, which can be used as a food preservative[3].
CAS Number
1173021-18-5
Product Name Alternative
Lactic acid (sodium) -13C2
UNSPSC
12352211
Target
Bacterial; Endogenous Metabolite; Hydroxycarboxylic Acid Receptor (HCAR) ; Isotope-Labeled Compounds
Related Pathways
Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer
Smiles
[13CH3][13C]([H])(C(O[Na])=O)O
Molecular Formula
C 13C2H5NaO3
Molecular Weight
114.05
References & Citations
[1]Lucia Longhitano, et al. Lactate Rewrites the Metabolic Reprogramming of Uveal Melanoma Cells and Induces Quiescence Phenotype. Int J Mol Sci. 2022 Dec 20;24 (1) :24.|[2]Qiang Feng, et al. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity. Nat Commun. 2022 Sep 6;13 (1) :4981. |[3]Sallam KI. Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon. Food Control. 2007 May;18 (5) :566-575.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported