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Colterol (hydrochloride) -d9

CAT: 0804-HY-W710337Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W710337Size:1 Each
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Description
Colterol hydrochloride-d9 is the deuterium labeled Colterol hydrochloride. Colterol hydrochloride is the hydrochloride salt form of Colterol (HY-128510). Colterol hydrochloride is the agonist for adrenergic receptor, and exhibits good affinity to β1-adrenoreceptor (heart) and β2-adrenoreceptor (lung) with IC50 of 645 nM and 147 nM. Colterol hydrochloride exhibits potential as a bronchodilator[1][2].
CAS Number
2714484-83-8
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Smiles
OC1=C(C=CC(C(O)CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C1)O.Cl
Molecular Formula
C12H11D9ClNO3
Molecular Weight
270.80
References & Citations
[1]Kusayama T, et al., Binding of a catechol derivative of denopamine (T-0509) and N-tert-butylnoradrenaline (Colterol) to beta 1- and beta 2-adrenoceptors. Biol Pharm Bull. 1994 Aug;17 (8) :1023-7. |[2]Walker SB, et al., Bitolterol mesylate: a beta-adrenergic agent. Chemistry, pharmacokinetics, pharmacodynamics, adverse effects and clinical efficacy in asthma. Pharmacotherapy. 1985 May-Jun;5 (3) :127-37.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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