4-Epitetracycline-d6

• Description:

  4-Epitetracycline-d6 is deuterated labeled 4-Epitetracycline hydrochloride (HY-136443) 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107) . Tetracycline can undergo epimerization insolution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity.

• UNSPSC:

  12352005

• Target:

  Antibiotic; Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C (C2=CC=C1) C (C3=C ([C@@] (O) ([C@]4 (C[C@@]3 ([C@@]2 (O) C) [H]) [H]) C (C (C (N) =O) =C ([C@@H]4N (C ([2H]) ([2H]) [2H]) C ([2H]) ([2H]) [2H]) O) =O) O) =O

• Molecular Formula:

  C22H18D6N2O8

• Molecular Weight:

  450.47

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lin Z, et al. Effects of two ecological earthworm species on tetracycline degradation performance, pathway and bacterial community structure in laterite soil. J Hazard Mater. 2021 Jun 15;412:125212.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported