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Dimebutic acid-d6

CAT: 0804-HY-W699526-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W699526-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dimebutic acid-d6 (NSC-16045-d6; NSC-741804-d6) is the deuterium labeled Dimebutic acid. Dimebutic acid is a fatty acid derivative. Dimebutic acid is an orally active short-chain fatty acid. Dimebutic acid stimulates fetal globin production and alters the balance of Bcl family proteins. Dimebutic acid prolongs red blood cell survival. Dimebutic acid exhibits toxicity in rats. Dimebutic acid is used in the study of β-thalassemia and sickle cell disease[1][2][3].
CAS Number
101419-75-4
Product Name Alternative
NSC-16045-d6; NSC-741804-d6
UNSPSC
12352211
Target
Bcl-2 Family; Isotope-Labeled Compounds
Related Pathways
Apoptosis; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Smiles
OC(C(C([2H])([2H])[2H])(CC)C([2H])([2H])[2H])=O
Molecular Formula
C6H6D6O2
Molecular Weight
122.20
References & Citations
[1]Dr Susan P. Perrine MD, et al. Evaluation of Safety and Pharmacokinetics of Sodium 2,2 Dimethylbutyrate, a Novel Short Chain Fatty Acid Derivative, in a Phase 1, Double-Blind, Placebo-Controlled, Single-Dose, and Repeat-Dose Studies in Healthy Volunteers.Clinical Pharmacology Volume51, Issue8 August 2011 Pages 1186-1194|[2]Parise RA, et al. Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Feb 1;862 (1-2) :168-74.|[3]Terse PS, et al. Short-term toxicity study of ST-20 (NSC-741804) by oral gavage in Sprague-Dawley rats. Toxicol Pathol. 2011 Jun;39 (4) :614-22.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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