Halometasone

• Description:

  Halometasone is a corticosteroid compound that can reduce the expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP) . Halometasone can be used in research on psoriasis and eczematous skin diseases[1].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H312, H332, H351

• Target:

  Leukotriene Receptor

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Purity:

  98.47

• Smiles:

  F[C@@]12[C@](C[C@@H](C([C@@]2(C=C3Cl)C)=CC3=O)F)([H])[C@@]4([H])[C@](C[C@@H]1O)([C@](O)([C@@H](C4)C)C(CO)=O)C

• Molecular Formula:

  C22H27ClF2O5

• Molecular Weight:

  444.90

• Precautions:

  H302, H312, H332, H351

• References & Citations:

  [1]Zhu J W, et al. Role of VEGF receptors in normal and psoriatic human keratinocytes: evidence from irradiation with different UV sources[J]. PLoS One, 2013, 8 (1) : e55463.|[2]Cao J, et al. Effect of halometasone cream combined with Simiao pill on the therapeutic effect and expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP) in patients with eczema, and the factors influencing its clinical efficacy. Ann Palliat Med. 2021 Nov;10 (11) :11643-11652.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• Isoform:

  LTB4

• CAS Number:

  [50629-82-8]