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γ-Dodecanolactone

CAT: 0804-HY-W275481-01Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-W275481-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
γ-Dodecanolactone is a γ-lactone compound. γ-Dodecanolactone exhibits inhibitory activity against CYP1A2 with an IC50 value of 58 µM and a pIC50 value of 4.24. γ-Dodecanolactone can be used in the research of diseases related to the CYP1A2 enzyme[1].
CAS Number
[2305-05-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.15
Smiles
O=C1OC(CCCCCCCC)CC1
Molecular Formula
C12H22O2
Molecular Weight
198.30
Precautions
H315, H319, H335
References & Citations
[1]Korhonen LE, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48 (11) :3808-15.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
CYP1

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