3-Methyluracil

• Description :

  3-Methyluracil (Compound 5) is a pyrimidine heterocyclic compound. 3-Methyluracil can be isolated from Cordyceps bassiana. 3-Methyluracil has anti-inflammatory activity. 3-Methyluracil inhibits Luciferase (HY-P1004) activity induced by NF-κB and AP-1 and reduces the mRNA levels of COX-2 and TNF-α. 3-Methyluracil can be used for inflammatory diseases research[1].

• CAS Number :

  [608-34-4]

• UNSPSC :

  12352005

• Hazard Statement :

  H351

• Target :

  COX; TNF Receptor

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology

• Purity :

  95.0

• Smiles :

  O=C1C=CNC(=O)N1C

• Molecular Formula :

  C5H6N2O2

• Molecular Weight :

  126.12

• Precautions :

  H351

• References & Citations :

  [1]Suh W, et al. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity. Biomol Ther (Seoul) . 2017 Mar 1;25 (2) :165-170.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• Isoform :

  COX-2