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DS02312223

CAT: 0804-HY-W1126235-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W1126235-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DS02312223 (D223) is a molecular glue that promotes the binding of RAS to PI3Kα, thereby enhancing glucose uptake in the absence of insulin. DS02312223 is used in diabetes research[1].
CAS Number
2253733-45-6
Product Name Alternative
D223
UNSPSC
12352005
Target
Molecular Glues
Related Pathways
PROTAC
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
CC(C)(OC(NCCOCCOC1=C(C=CC=C1)C2=C3SC=CC3=C(N=N2)NC4=C(C=C(C=C4)CC(N)=O)F)=O)C
Molecular Formula
C29H32FN5O5S
Molecular Weight
581.66
References & Citations
[1]Terayama K, et al. Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin. Science. 2025 Jul 24;389 (6758) :402-408.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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