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BDPI

CAT: 0804-HY-W112239-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W112239-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models[1].
CAS Number
1083009-44-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Cancer
Purity
98.10
Smiles
CC(C(I)=C1C)=C(N1[B-]2(F)F)C(C3=CC=CC=C3)=C4[N+]2=C(C)C(I)=C4C
Molecular Formula
C19H17BF2I2N2
Molecular Weight
575.97
Precautions
H302, H315, H319, H335
References & Citations
[1]Zou J, et al., BODIPY Derivatives for Photodynamic Therapy: Influence of Configuration versus Heavy Atom Effect. ACS Appl Mater Interfaces. 2017 Sep 27;9 (38) :32475-32481.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported