Rizatriptan

• Description:

  Rizatriptan (MK 462 free base) is an orally active, potent and selective 5-HT1D receptor agonist. Rizatriptan is promising for research of migraine[1].

• Product Name Alternative:

  MK 462 (free base)

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  5-HT Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Smiles:

  CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3

• Molecular Formula:

  C15H19N5

• Molecular Weight:

  269.34

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Street LJ, et al. Synthesis and serotonergic activity of N, N-dimethyl-2-[5- (1,2,4-triazol-1-ylmethyl) -1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. J Med Chem. 1995 May 12;38 (10) :1799-810.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  5-HT1 Receptor

• CAS Number:

  [144034-80-0]