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Acivicin (Standard)

CAT: 0804-HY-W016586RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W016586RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway[1][2][3].
CAS Number
42228-92-2
Product Name Alternative
AT-125 (Standard) ; U-42126 (Standard)
UNSPSC
12352005
Target
Parasite; Reference Standards; γ-Glutamyl Transferase (GGT)
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection
Smiles
ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1
Molecular Formula
C5H7ClN2O3
Molecular Weight
178.57
References & Citations
[1]Kreuzer J, et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition. Chem Sci. 2014 Dec 1;6 (1) :237-245. Epub 2014 Sep 26.|[2]Chikhale EG, et al. Carrier-mediated transport of the antitumor agent acivicin across the blood-brain barrier. Biochem Pharmacol. 1995 Mar 30;49 (7) :941-5.|[3]Delphine Waniusiow, et al. Toluene-induced hearing loss in acivicin-treated rats. Neurotoxicol Teratol. May-Jun 2008;30 (3) :154-60.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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