Benzylmethyl ether

• Description :

  Benzylmethyl ether is a derivative of HY-B0892 (Benzyl alcohol) . Benzylmethyl ether is an aromatic alcohol, a colorless liquid with a mild aromatic odor. Benzylmethyl ether is an inhibitor of P450 enzyme. Benzylmethyl ether mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H226

• Target :

  Cytochrome P450; Drug Derivative; Toll-like Receptor (TLR)

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; Others

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Others

• Purity :

  98.70

• Smiles :

  COCC1=CC=CC=C1

• Molecular Formula :

  C8H10O

• Molecular Weight :

  122.16

• Precautions :

  H226

• References & Citations :

  [2]Du K, et al. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. Food Chem Toxicol. 2015 Dec;86:253-61.|[3]Cai C, et al. Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology. 2014 Sep;60 (3) :990-1002.|[1]Friedlander G, et al. Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells. Biochim Biophys Acta. 1987 Oct 2;903 (2) :341-8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  TLR4

• CAS Number :

  [538-86-3]