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Benzylmethyl ether

CAT: 0804-HY-W012837-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W012837-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Benzylmethyl ether is a derivative of HY-B0892 (Benzyl alcohol). Benzylmethyl ether is an aromatic alcohol, a colorless liquid with a mild aromatic odor. Benzylmethyl ether is an inhibitor of P450 enzyme. Benzylmethyl ether mediated Toll-Like Receptor 4 to reduce the inflammatory response of liver injury in mice[1][2][3].
CAS Number
538-86-3
UNSPSC
12352005
Hazard Statement
H226
Target
Cytochrome P450; Drug Derivative; Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Purity
98.70
Smiles
COCC1=CC=CC=C1
Molecular Formula
C8H10O
Molecular Weight
122.16
Precautions
H226
References & Citations
[2]Du K, et al. Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. Food Chem Toxicol. 2015 Dec;86:253-61.|[3]Cai C, et al. Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology. 2014 Sep;60 (3) :990-1002.|[1]Friedlander G, et al. Benzyl alcohol increases membrane fluidity and modulates cyclic AMP synthesis in intact renal epithelial cells. Biochim Biophys Acta. 1987 Oct 2;903 (2) :341-8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
TLR4

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