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Pent-4-yn-1-ol

CAT: 0804-HY-W010642-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W010642-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pent-4-yn-1-ol is a PROTAC linker. Pent-4-yn-1-ol can be used to synthesize PROTAC molecules (e.g. RD-23 ).
CAS Number
5390-04-5
Product Name Alternative
4-Pentyn-1-ol
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.61
Smiles
C#CCCCO
Molecular Formula
C5H8O
Molecular Weight
84.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Hualong M, et al. Discovery of a Selective and Orally Bioavailable RET Degrader with Effectiveness in Various Mutations. J Med Chem. 2025 Feb 13;68 (3) :2657-2679.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

4-Pentyn-1-ol

structure in first source

CAS Number5390-04-5
PubChem CID79346
IUPAC Namepent-4-yn-1-ol
Molecular FormulaC5H8O
Molecular Weight84.12
XLogP0.5
Topological Polar Surface Area20.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Heavy Atom Count6
Formal Charge0
Complexity57
SMILES
C#CCCCO
InChI
InChI=1S/C5H8O/c1-2-3-4-5-6/h1,6H,3-5H2
InChIKey
CRWVOXFUXPYTRK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-Pentyn-1-ol
CAS: 5390-04-5
CID: 79346
Formula: C5H8O
MW: 84.12
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight84.12
XLogP30.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass84.057514874
Monoisotopic Mass84.057514874
Topological Polar Surface Area20.2 Ų
Heavy Atom Count6
Formal Charge0
Complexity57.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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