Products for Research Use Only

7-Methoxy-1-tetralone

CAT: 0804-HY-W001925-01Size: 5 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W001925-01Size:5 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
7-Methoxy-1-tetralone is a potent antitumor agent. 7-Methoxy-1-tetralone inhibits cancer cell proliferation and migration, and induces hepatocellular carcinoma cell (HCC) apoptosis. 7-Methoxy-1-tetralone decreased the protein levels of NF-κB, matrix metallopeptidase 2 (MMP2) /MMP9, and p-AKT. 7-Methoxy-1-tetralone showed antitumor activity in nude mice and had no effect on body weight and liver, spleen and organ index[1].
CAS Number
6836-19-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Akt; Apoptosis; c-Met/HGFR; MMP; NF-κB
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCC1)C2=C1C=CC(OC)=C2
Molecular Formula
C11H12O2
Molecular Weight
176.22
Precautions
H302, H315, H319, H332, H335
References & Citations
[1]Wen Y, et al. 7-Methoxy-1-Tetralone Induces Apoptosis, Suppresses Cell Proliferation and Migration in Hepatocellular Carcinoma via Regulating c-Met, p-AKT, NF-κB, MMP2, and MMP9 Expression. Front Oncol. 2020 Feb 7;10:58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported