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Rabbit Polyclonal Antibody to Integrin beta 3

CAT: 1725-P23169-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P23169-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity) .
Product Name Alternative
ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61
Swiss Prot
P05106
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human ITGB3. AA range:621-670
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
Integrin beta 3
Bands Size
Calculated MW: 87 kDa; Observed MW: 87 kDa

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