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YH004

CAT: 0804-HY-P991530Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P991530Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YH004 is an anti-CD137 agonistic monoclonal antibody, with immunostimulating and antineoplastic activities. YH004 activates CD137 expressed on a variety of leukocyte subsets including activated T lymphocytes and natural killer cells. YH004 enhances CD137-mediated signaling and induces cytotoxic T-lymphocyte (CTL) proliferation, cytokine production and promotes anti-tumor response mediated by CTL. YH004 induces NK-mediated tumor cell killing and suppresses the immunosuppressive activity of regulatory T cells. YH004 can be studied in anticancer research[1].
UNSPSC
12352203
Target
Biochemical Assay Reagents
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
References & Citations
[1]Chaoshe Guo, et al., Abstract 522: Optimization of novel anti-4-1BB antibodies on Biocytogen's in vivo drug screening platform.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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CatalogName
T9901A-1796-01YH004

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