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JST-TfR09

CAT: 0804-HY-P991381Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P991381Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control.
Product Name Alternative
PPMX-T003
UNSPSC
12352203
Target
Ferroptosis; Reactive Oxygen Species (ROS) ; Transferrin Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[JST-TfR09]
References & Citations
[1]Fauzi YR, et al. Anti-transferrin receptor antibody (JST-TFR09/PPMX-T003) induces ferroptosis in adult T-cell leukemia/lymphoma (ATLL) cells. Biochem Biophys Res Commun. 2025 Apr 5;756:151564.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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