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CQY684

CAT: 0804-HY-P991342Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P991342Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CQY684 (PCA062 antibody) is a human monoclonal antibody (mAb) targeting CDH3/P-cadherin. CQY684 stabilizes the X-dimer of P-cadherin, promoting its endocytosis and directing it to lysosomal degradation. CQY684 can be used in Breast, esophageal, and head and neck cancers research[1].
Product Name Alternative
PCA062 antibody
UNSPSC
12352203
Target
Cadherin
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[CQY684]
References & Citations
[1]Tam A, et al. Using genome-wide CRISPR screen to understand resistance mechanisms to PCA062, a P-cadherin targeting antibody-drug conjugate[J]. Cancer Research, 2019, 79 (13_Supplement) : 4743-4743.|[2]Xie B, et al. Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody. Nat Commun. 2025 Jan 29;16 (1) :1157.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

Alternative Products

CatalogName
T9901A-1609-01CQY684

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