Products for Research Use Only
RegisterLogin

Nezutatug

CAT: 0804-HY-P991237-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P991237-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Nezutatug (HMBD-001) is a humanized IgG1 monoclonal antibody inhibitor targeting HER3. Nezutatug inhibits the dimerization of HER3 and inhibits the growth, proliferation and other activities of tumor cells. Nezutatug is promising for research of cancers, such as pancreatic cancer and non-small cell lung cancer[1][2].
CAS Number
2673271-78-6
Product Name Alternative
HMBD-001
UNSPSC
12352203
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.9
Smiles
[Nezutatug]
Molecular Weight
(144.89 kDa)
References & Citations
[1]Pavlakis N, et al. 88TiP A phase Ib study of HMBD-001, a monoclonal antibody targeting HER3, with or without chemotherapy in patients with genetic aberrations in HER3 signaling[J]. Annals of Oncology, 2023, 34: S1501.|[2]Idowu O, et al. 688P Pharmacokinetics of HMBD-001, a human monoclonal antibody targeting HER3, a CRUK first-in-human phase I trial in patients with advanced solid tumours[J]. Annals of Oncology, 2023, 34: S480.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

Alternative Products

CatalogName
T81679-01Nezutatug
MBS1580395-01Research Grade Nezutatug
GTR18333547-01Nezutatug Antibody
E55B1048Nezutatug (Reference antibody)
ICH5710-50mgNezutatug Biosimilar - Research Grade
A138112Nezutatug Biosimilar (Monoclonal, IgG1)
GTR18780193-01(Nezutatug) Biosimilar Reference Antibody
GTR18695978-01Nezutatug Human Monoclonal Antibody
MBS1881453-01Anti-Her3 (nezutatug biosimilar) mAb
12-90230B-100Biotinylated Anti-Her3 (nezutatug biosimilar) mAb

Popular Products