Tetrapeptide-21

• Description:

  Tetrapeptide-21 is a bioactive peptide composed of four amino acids. Tetrapeptide-21 effectively enhances the vitality of human dermal fibroblasts. Tetrapeptide-21 upregulates the expression of key extracellular matrix (ECM) genes and promotes the synthesis of ECM proteins (such as type I collagen, hyaluronic acid synthase 1, and fibronectin) . Tetrapeptide-21 has the efficacy of anti-wrinkle and improving skin elasticity, and has been reported to be used as a cosmetic ingredient[1][2].

• UNSPSC:

  12352209

• Target:

  Collagen

• Related Pathways:

  Cytoskeleton

• Field of Research:

  Metabolic Disease

• Purity:

  98.87

• Solubility:

  H2O : ≥ 200 mg/mL

• Smiles:

  NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(NCC(O)=O)=O)=O)=O

• Molecular Formula:

  C15H27N5O7

• Molecular Weight:

  389.40

• References & Citations:

  [1]Beldio Research GmbH, et al. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics 2017, 4 (2), 16|[2]Paccola AGL, et al. Synergistic Effects of Injectable Platelet-Rich Fibrin and Bioactive Peptides on Dermal Fibroblast Viability and Extracellular Matrix Gene Expression: An In Vitro Study. Molecules. 2025 Aug 19;30 (16) :3415.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [960608-17-7]