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DT-2 (acetate)

CAT: 0804-HY-P2692B-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2692B-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DT-2 is a potent and selective inhibitor of the cGMP-dependent protein kinase (PKG) . DT-2 inhibits PKG catalyzed phosphorylation (Ki: 12.5 nM) [1].
UNSPSC
12352209
Target
PKG
Related Pathways
Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.64
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]3N(CCC3)C([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CNC([C@@H](N)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C.O=C(O)C
Molecular Formula
C154H287N53O55
Molecular Weight
3761.25
References & Citations
[1]Pinkse MWH, et al. Mode of action of cGMP-dependent protein kinase-specific inhibitors probed by photoaffinity cross-linking mass spectrometry. J Biol Chem. 2009 Jun 12;284 (24) :16354-16368.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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