Lytx-Pa2a

Lytx-Pa2a (Lycotoxin-Pa2a) is a peptide inhibitor against bacterial membranes and TLR4 receptor. Lytx-Pa2a exerts antimicrobial effects via non-competitive disruption of outer/cytoplasmic membranes and suppression of LPS-induced TLR4/NF-κB signaling. Lytx-Pa2a is promising for research of bacterial infection and inflammation-related disease (e.g., sepsis) [1].

Lycotoxin-Pa2a; TBIU041425

12352209

Bacterial; Toll-like Receptor (TLR)

Anti-infection; Immunology/Inflammation

COVID-19-immunoregulation

Inflammation/Immunology

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C314H494N94O91S8

7298.38

[1]Shin MK, et al. The Identification of a Novel Spider Toxin Peptide, Lycotoxin-Pa2a, with Antibacterial and Anti-Inflammatory Activities. Antibiotics (Basel) . 2023 Dec 7;12 (12) :1708.

Room temperature

Peptides

No Development Reported