Products for Research Use Only
RegisterLogin

VMAPRTLFL

CAT: 0804-HY-P11340Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P11340Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VMAPRTLFL is a 9-mer peptide derived from the signal peptide of HLA-G and can serve as a peptide ligand for HLA-E. VMAPRTLFL plays a crucial role in regulating the functions of adaptive natural killer (NK) cells. Specifically, VMAPRTLFL enriches FcεRγ- adaptive NK cells, upregulates the expression of CD25, and enhances their proliferative activity, antibody-dependent cellular cytotoxicity (ADCC), and IFN-γ release. VMAPRTLFL can be used in research related to human cytomegalovirus (HCMV) infection, transplant rejection, and pregnancy immunity[1].
CAS Number
202657-61-2
UNSPSC
12352209
Target
MHC
Related Pathways
Immunology/Inflammation
Field of Research
Infection; Inflammation/Immunology
Smiles
CC(C)[C@H](N)C(N[C@@H](CCSC)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(O)=O)CC(C)C)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C49H82N12O11S
Molecular Weight
1047.31
References & Citations
[1]Rölle A, et al. Distinct HLA-E Peptide Complexes Modify Antibody-Driven Effector Functions of Adaptive NK Cells. Cell Rep. 2018 Aug 21;24 (8) :1967-1976.e4.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MHC I

Related Products

CatalogName
HY-P705387-01HLA-E*0103 CMV UL40 Complex, Human (Biotinylated, VMAPRTLLL, HEK293, His-Avi)
HY-P77760-01HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human (HEK293, His-Avi)
HY-P77758-01HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human (HEK293, His-Avi)
HY-P77761HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human (Biotinylated, HEK293, His-Avi)
HY-P77759HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human (Biotinylated, HEK293, His-Avi)
HY-P705389-01HLA-E*0103 CMV UL40 Complex, Human (Biotinylated, VMAPRTVLL, HEK293, His-Avi)
HY-P705388-01HLA-E*0103 CMV UL40 Complex, Human (Biotinylated, VMAPRTVIL, HEK293, His-Avi)

Alternative Products

CatalogName
GTR19150238-01VMAPRTLFL

Popular Products