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FGF7p

CAT: 0804-HY-P11162Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P11162Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF7p is a small molecule peptide and a potential bladder protector. FGF7p can activate downstream signaling pathways of FGFR2 in the urinary tract epithelium (pFRS2α, pAKT and pERK) . FGF7p alleviates cyclophosphamide induced apoptosis and tissue damage in urinary tract epithelial cells by activating AKT and its downstream anti apoptotic targets (pBAD, pS6/mTORC1) . FGF7p has the advantages of low cost, good stability, and high purity. FGF7p is commonly used in the study of inflammatory conditions[1].
CAS Number
2758194-43-1
UNSPSC
12352209
Target
Akt; Apoptosis; ERK; FGFR; mTOR
Related Pathways
Apoptosis; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CC(N)=O)C(NCC(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=C(C=C5)O)N
Molecular Formula
C95H138N26O28S
Molecular Weight
2124.33
References & Citations
[1]Narla ST, et al. FGF7 peptide (FGF7p) mimetic mitigates bladder urothelial injury from cyclophosphamide. Physiol Rep. 2022 Apr;10 (7) :e15241.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Akt; ERK; FGFR2; mTORC1

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