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Peptide P2.2

CAT: 0804-HY-P11040Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P11040Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Peptide P2.2, a non-ribosomal peptide, is an antimicrobial peptide. Peptide P2.2 has potent antibacterial activity with MIC50s of 4 and 32 μM for V. parahaemolyticus and V. alginolyticus, respectively. Peptide P2.2 increases synergistic antibacterial effects with antibiotics (such as Ofloxacin (HY-B0125) and Linezolid (HY-10394) ) with negligible hemolytic activity. Peptide P2.2 disrupts bacterial membranes and increases permeability by modulating proteins involved in the type VI and III secretion systems. Peptide P2.2 can be used for bacterial infections research[1].
UNSPSC
12352209
Target
Antibiotic; Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C64H116N18O20
Molecular Weight
1457.71
References & Citations
[1]Yang CL, et al. Discovery of naturally inspired antimicrobial peptides using deep learning. Bioorg Chem. 2025 Jun 15;160:108444.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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