Tet1 peptide

• Description:

  Tet1 peptide (HLNILSTLWKYR) is neuron-specific ligand for GT1B gangliosides. And a cysteine is usually add to its C-terminus (which refers to HLNILSTLWKYRC (HY-P11094) ) for peptide conjugation and drug delivery reseraches.

• UNSPSC:

  12352209

• Target:

  TET Protein

• Related Pathways:

  Epigenetics

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Smiles:

  O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CNC=N4)N

• Molecular Formula:

  C73H114N20O17

• Molecular Weight:

  1543.81

• References & Citations:

  [1]Wang P, et al. Systemic delivery of BACE1 siRNA through neuron-targeted nanocomplexes for treatment of Alzheimer's disease. J Control Release. 2018 Jun 10;279:220-233.|[2]Zhang Y, et al. Targeted delivery of Tet1 peptide functionalized polymersomes to the rat cochlear nerve. Int J Nanomedicine. 2012;7:1015-22.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [270919-17-0]