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APO-15

CAT: 0804-HY-P10943-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P10943-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APO-15 is a fluorogenic imaging agent targeting phosphatidylserine (PS) exposed on the cell membrane of apoptotic cells. APO-15 can selectively bind to apoptotic cells, enabling staining and imaging of apoptotic cells in a calcium-independent and wash-free manner. APO-15 is promising for research of inflammatory diseases and cancers[1].
CAS Number
[3051946-11-0]
UNSPSC
12352209
Target
Ser/Thr Kinase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Purity
99.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=C2N(C(C)=C1)[B-](F)(F)[N+]3=C(C)C=C(C)C3=C2C4=CC=CC(C(NC5=CC=CC=C65)=C6C[C@@H](C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CNC8=C7C=CC=C8)C9=O)=O)CCCCN)=O)CCCCN)=O)=O)=O)NC([C@H](CC%10=CC=CC=C%10)N9)=O)=C4
Molecular Formula
C70H85BF2N16O7
Molecular Weight
1311.33
References & Citations
[1]Barth ND, et al. A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nat Commun. 2020 Aug 12;11 (1) :4027.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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