Products for Research Use Only
RegisterLogin

CNI103

CAT: 0804-HY-P10889Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P10889Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CNI103 is a highly potent and metabolically stable cell-permeable peptide inhibitor of calcineurin. CNI103 selectively blocks the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing NFATc3 activation in vitro and in vivo. CNI103 can be used to study acute respiratory distress syndrome (ARDS) and other inflammatory diseases[1].
CAS Number
2366279-86-7
UNSPSC
12352209
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)(O)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CNC=N1)C(N[C@@H](C(N[C@H](C(NCCOCCOCC(N[C@@H](CCCCNC(CC[C@H](NC([C@H](NC([C@H](CCCNC(N)=N)NC([C@@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC2=CC=C3C(C=CC=C3)=C2)N4)=O)=O)=O)=O)CCCNC(N)=N)=O)C(N[C@H](CC5=CC=CC=C5)C4=O)=O)=O)C(N)=O)=O)=O)CO)=O)CC(C)C)=O)=O)CCC(N)=O)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)=O)=O)C(C)(C)C)C6=CC=NC(Cl)=C6Cl
Molecular Formula
C116H180Cl2N36O26
Molecular Weight
2565.80
References & Citations
[1]Dougherty PG, et al. A Peptidyl Inhibitor that Blocks Calcineurin-NFAT Interaction and Prevents Acute Lung Injury. J Med Chem. 2020 Nov 12;63 (21) :12853-12872.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-RS02886CNIH3 Human Pre-designed siRNA Set A

Alternative Products

CatalogName
TP3040-01CNI103

Popular Products