Polyglutamine binding peptide 1

CAT: 0804-HY-P10818-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-P10818-01Size:500 µg
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Description
Polyglutamine binding peptide 1 (QBP1) is a peptide inhibitor of polyglutamine (polyQ) . Polyglutamine binding peptide 1 inhibits polyQ protein aggregation in vitro and suppresses polyQ-induced cell death in cell culture[1].
CAS Number
[274914-75-9]
UNSPSC
12352209
Target
Huntingtin
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N7[C@@H](CCC7)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
Molecular Formula
C72H90N16O16
Molecular Weight
1435.58
References & Citations
[1]Yoshitaka Nagai, et al. Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila. Hum Mol Genet. 2003 Jun 1;12 (11) :1253-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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