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Phoyunbene B

CAT: 0804-HY-N9778Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N9778Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phoyunbene B is a similar substance to Resveratrol. Phoyunbene B exhibits stronger growth inhibitory activity against human liver cancer cells HepG2 compared to Resveratrol. Phoyunbene B induces G2/M phase cell cycle arrest and apoptosis. Phoyunbene B increases Bax/Bcl-2 and activates Caspase-3. Phoyunbene B inhibits the invasion and migration of cancer cells. Phoyunbene B can be used for research on liver cancer[1].
CAS Number
886747-62-2
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Apoptosis; Bcl-2 Family; Caspase; Drug Derivative
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Smiles
COC1=CC(O)=CC(/C=C/C2=C(C(OC)=C(C=C2)O)OC)=C1
Molecular Formula
C17H18O5
Molecular Weight
302.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Wang G, et al. A resveratrol analog, phoyunbene B, induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells. Bioorg Med Chem Lett. 2012 Mar 1;22 (5) :2114-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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