Aloesone

CAT: 0804-HY-N8559-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N8559-01Size:1 mg
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Description
Aloesone is a phenolic compound. Aloesone can inhibit the production of ROS, the release of NO, M1 polarization, and apoptosis in RAW264.7 cells stimulated by LPS (HY-D1056) . Aloesone has anti-inflammatory and antioxidant activities[1][2].
CAS Number
[40738-40-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(CC(C)=O)OC2=CC(O)=CC(C)=C12
Molecular Formula
C13H12O4
Molecular Weight
232.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Reza Nazifi SM, et al. Antioxidant properties of Aloe vera components: a DFT theoretical evaluation. Free Radic Res. 2019 Aug;53 (8) :922-931.|[2]Wang Y, et al. Multiple Beneficial Effects of Aloesone from Aloe vera on LPS-Induced RAW264.7 Cells, Including the Inhibition of Oxidative Stress, Inflammation, M1 Polarization, and Apoptosis. Molecules. 2023 Feb 8;28 (4) :1617.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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