Products for Research Use Only
RegisterLogin

Amicoumacin B

CAT: 0804-HY-N8261-01Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N8261-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2) . Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 µg/mL) . Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2].
CAS Number
77674-99-8
UNSPSC
12352005
Target
Bacterial; TGF-beta/Smad
Related Pathways
Anti-infection; Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Infection
Smiles
O=C1C2=C(O)C=CC=C2C[C@@](O1)([H])[C@H](CC(C)C)NC([C@@H](O)[C@@H](O)[C@@H](N)CC(O)=O)=O
Molecular Formula
C20H28N2O8
Molecular Weight
424.44
References & Citations
[1]Shi WP, et al. Amicoumacins from a desert bacterium: quorum sensing inhibitor against Chromobacterium violaceum. Nat Prod Res. 2021 Dec;35 (23) :5508-5512.|[2]Sun W, et al. Nocardia jinanensis sp. nov., an amicoumacin B-producing actinomycete. Int J Syst Evol Microbiol. 2009 Feb;59 (Pt 2) :417-20.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-127072-01Amicoumacin A
HY-N14791Amicoumacin C
HY-W777997Nocardicin B
HY-W713570-01Nectandrin B
HY-W777995-01Clindamycin B
HY-W013935-01Bisphenol B
HY-N8507Tunicamycin B
HY-N7046-01Silybin B
HY-162836-01Rifamycin B
HY-N7637-01Tubuloside B

Alternative Products

CatalogName
T23725-01Amicoumacin A
AR-A06138-01Amicoumacin C
AR-A06137-01Amicoumacin B
T23725L-01Amicoumacin A FA

Popular Products