Aselacin A

CAT: 0804-HY-N5170Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N5170Size:1 Each
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Description
Aselacin A targets endothelin-1 receptor (ET-1 receptor), inhibits the the binding of ET-1 to ETA receptor and ETB receptor. Aselacin A inhibits the ET-1 binding to bovine atrial membrane and porcine cerebral membrane with IC50 of 22 μg/mL and 20 μg/mL. Aselacin A can be used for research of cardiovascular diseases[1].
CAS Number
[156223-06-2]
UNSPSC
12352005
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C1O[C@@H]([C@@H](C(NCCC(N[C@H](CC2=CNC3=C2C=CC=C3)C(N[C@H](CO)C(NC1)=O)=O)=O)=O)NC([C@@H](CCC(N)=O)NC(CCCCCCCC(/C=C/C=C/CCCCC)O)=O)=O)C
Molecular Formula
C46H68N8O11
Molecular Weight
909.08
References & Citations
[1]Jackson M, et al., Aselacins, novel compounds that inhibit binding of endothelin to its receptor. I. The producing organism, fermentation and biological activity. J Antibiot (Tokyo) . 1994 May;47 (5) :523-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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