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Stigmalactam

CAT: 0804-HY-N16535Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N16535Size:1 Each
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Description
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP) . Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research[1].
CAS Number
289499-72-5
UNSPSC
12352005
Target
Apoptosis; Caspase; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
O=C1NC2=CC3=CC=C(C=C3C4=C2C1=C(OC)C(OC)=C4OC)O
Molecular Formula
C18H15NO5
Molecular Weight
325.32
References & Citations
[1]Banjerdpongchai R, et al. Stigmalactam from Orophea enterocarpa induces human cancer cell apoptosis via a mitochondrial pathway. Asian Pac J Cancer Prev. 2014;15 (23) :10397-400.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
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