Cochliomycin A

• Description :

  Cochliomycin A ((+) -Cochliomycin A) can be isolated from Gorgonian-Derived Fungus Cochliobolus lunatus. Cochliomycin A has antifouling activity (EC50: 1.2 μg/mL) . Cochliomycin A inhibits barnacle larval settlement by stimulating the NO/cGMP pathway. Cochliomycin A also has moderate antibacterial activity against S. aureus[1][2].

• Product Name Alternative :

  (+) -Cochliomycin A

• UNSPSC :

  12352005

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  OC1=C(C(O[C@H](C/C=C/[C@@](O2)([H])[C@@]3([H])OC2(C)C)C)=O)C(/C=C/C[C@@H]3O)=CC(OC)=C1

• Molecular Formula :

  C22H28O7

• Molecular Weight :

  404.45

• References & Citations :

  [1]Shao CL, et al. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J Nat Prod. 2011 Apr 25;74 (4) :629-33. |[2]Wang KL, et al. Cochliomycin A inhibits the larval settlement of Amphibalanus amphitrite by activating the NO/cGMP pathway. Biofouling. 2016;32 (1) :35-44.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [1278520-07-2]