Sphingosine kinase 1a Active from Mouse

• Description:

  Sphingosine kinase 1a Active from Mouse_x000D_ Catalog number: B2019700_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 ug_x000D_ Molecular Weight or Concentration: 47.1 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −70°C_x000D_ Keywords: SK1, SPHK1, SPK 1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Oh YS, Bae SS, Park JB, Ha SH, Ryu SH, Suh PG. Mouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 Residue PLoS One. 2015 Dec 7;10(12):e0143695._x000D_ 2: Venkataraman K, Thangada S, Michaud J, Oo ML, Ai Y, Lee YM, Wu M, Parikh NS, Khan F, Proia RL, Hla T. Extracellular export of sphingosine kinase-1a contributes to the vascular S1P gradient Biochem J. 2006 Aug 1;397(3):461-71._x000D_ 3: Li H, Li Y, Wang Y, Sheng Y. Neuronal protective effect of Artemisinin in ischemic stroke: Achieved by blocking lysine demethylase 1A-mediated demethylation of sphingosine kinase 2 Brain Res. 2024 Dec 31:149442._x000D_ 4: Yokota S, Taniguchi Y, Kihara A, Mitsutake S, Igarashi Y. Asp177 in C4 domain of mouse sphingosine kinase 1a is important for the sphingosine recognition FEBS Lett. 2004 Dec 3;578(1-2):106-10._x000D_ 5: Murate T, Banno Y, T-Koizumi K, Watanabe K, Mori N, Wada A, Igarashi Y, Takagi A, Kojima T, Asano H, Akao Y, Yoshida S, Saito H, Nozawa Y. Cell type-specific localization of sphingosine kinase 1a in human tissues J Histochem Cytochem. 2001 Jul;49(7):845-55._x000D_ 6: Furuya H, Wada M, Shimizu Y, Yamada PM, Hannun YA, Obeid LM, Kawamori T. Effect of sphingosine kinase 1 inhibition on blood pressure FASEB J. 2013 Feb;27(2):656-64._x000D_ 7: Minashima T, Campbell KA, Hadley SR, Zhang Y, Kirsch T. The role of ANK interactions with MYBBP1a and SPHK1 in catabolic events of articular chondrocytes Osteoarthritis Cartilage. 2014 Jun;22(6):852-61._x000D_ 8: Ye Q, Zhou Y, Zhao C, Xu L, Ping J. Salidroside Inhibits CCl(4)-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1 Front Pharmacol. 2021 May 13;12:677810._x000D_ 9: Billich A, Bornancin F, Dévay P, Mechtcheriakova D, Urtz N, Baumruker T. Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases J Biol Chem. 2003 Nov 28;278(48):47408-15._x000D_ 10: von Wnuck Lipinski K, Weske S, Keul P, Peters S, Baba HA, Heusch G, Gräler MH, Levkau B. Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis Blood. 2017 Dec 21;130(25):2786-2798. _x000D_ _x000D_ Products Related to Sphingosine kinase 1a Active from Mouse can be found at Proteins

• Short Description:

  Catalog Number: B2019700 (5 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5