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Coumestan

CAT: 0804-HY-N15662Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N15662Size:1 Each
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Description
Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol , Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective[1][2][3][4][5].
CAS Number
479-12-9
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Smiles
O=C1C2=C(C3=C(O1)C=CC=C3)OC4=C2C=CC=C4
Molecular Formula
C15H8O3
Molecular Weight
236.22
References & Citations
[1]Tabbasum MT, R S. Emerging Coumestans in Cancer Therapy With Mechanistic Insights and Clinical Potential. Arch Pharm (Weinheim) . 2025 Jul;358 (7) :e70058. doi: 10.1002/ardp.70058. |[2]Kim JE, et al. Coumestrol Epigenetically Suppresses Cancer Cell Proliferation: Coumestrol Is a Natural Haspin Kinase Inhibitor. Int J Mol Sci. 2017 Oct 24;18 (10) :2228.|[3]Lun S, et al. Therapeutic potential of coumestan Pks13 inhibitors for tuberculosis. Antimicrob Agents Chemother. 2023 May 1;95 (5) :e02190-20. |[4]Seong SH, et al. Phytoestrogen Coumestrol Selectively Inhibits Monoamine Oxidase-A and Amyloid β Self-Aggregation. Nutrients. 2022 Sep 16;14 (18) :3822. |[5]Djafarou S, Boulebd H. The radical scavenger capacity and mechanism of prenylated coumestan-type compounds: a DFT analysis. Free Radic Res. 2022 Mar-Apr;56 (3-4) :273-281.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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