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Saringosterol

CAT: 0804-HY-N15574-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N15574-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Saringosterol is found in Sargassum muticum. Saringosterol is a LXR agonist that lowers cholesterol. saringosterol inhibits the mRNA and protein expression of peroxisome proliferator-activated receptor γ and CCAAT enhancer-binding protein α in 3T3-L1 cells. Saringosterol has anti-Mycobacterium tuberculosis activity. Saringosterol can be used in anti-obesity and anti-atherosclerosis research[1][2][3].
CAS Number
6901-60-6
UNSPSC
12352211
Target
Bacterial; LXR
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease; Cardiovascular Disease
Purity
90.0
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(C=C)(O)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
Molecular Formula
C29H48O2
Molecular Weight
428.69
References & Citations
[1]Chen Z, et al. 24 (S) -Saringosterol from edible marine seaweed Sargassum fusiforme is a novel selective LXRβ agonist. J Agric Food Chem. 2014 Jul 2;62 (26) :6130-7.|[2]Lee JA, et al. Anti-Obesity Activity of Saringosterol Isolated from Sargassum muticum (Yendo) Fensholt Extract in 3T3-L1 Cells. Phytother Res. 2017 Nov;31 (11) :1694-1701.|[3]Wächter GA, et al. Inhibition of Mycobacterium tuberculosis growth by saringosterol from Lessonia nigrescens. J Nat Prod. 2001 Nov;64 (11) :1463-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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