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Rabbit Monoclonal to ERAP1

CAT: 1725-P18775-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P18775-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.
Product Name Alternative
ALAP; Aminopeptidase PILS; APPILS; Arts1; Endoplasmic reticulum aminopeptidase 1; ERAAP; ERAAP1; Erap1; PILSA; PILSAP; ; ERAP1
Swiss Prot
Q9NZ08
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human ERAP1
Clonality
Monoclonal
Applications
WB; IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
ERAP1
Bands Size
Calculated MW: 107 kDa ; Observed MW: 100 kDa

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