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Talaromyketide B

CAT: 0804-HY-N15347Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N15347Size:1 Each
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Description
Talaromyketide B is a polyketide compound with anti-inflammatory activity, discovered in the soil bacterium Talaromyces sp. KYS-41. Talaromyketide B inhibits the activation of the NF-κB and MAPK signaling pathways and dose-dependently suppresses pro-inflammatory cytokines, such as IL-1β, IL-6, IL-10, and TNF-α, as well as the transcriptional activity of inflammatory mediators, including iNOS and COX-2. Talaromyketide B holds potential for research in the fields of immunity and inflammatory diseases[1].
UNSPSC
12352211
Target
COX; Interleukin Related; NF-κB; NO Synthase; p38 MAPK; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; NF-κB
Field of Research
Inflammation/Immunology
Smiles
O=C1C2=CC(OC)=CC(O)=C2C(C(OCC)=O)(O)C=C1C
Molecular Formula
C15H16O6
Molecular Weight
292.28
References & Citations
[1]Jia DX, et al. Talaromyketides A-I: Nine polyketides with anti-inflammatory activity from a soil fungus Talaromyces sp. KYS-41. Bioorg Chem. 2025 Apr;157:108275.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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