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Convolamine

CAT: 0804-HY-N15339Size: 1 EachDry Ice: NoHazardous: No
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Description
Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC50 = 289 nM), exhibiting cognitive and neuroprotective properties[1][2].
CAS Number
500-56-1
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C(C=C1)=CC(OC)=C1OC)O[C@H](C[C@]2([H])CC3)C[C@]3([H])N2C
Molecular Formula
C17H23NO4
Molecular Weight
305.37
References & Citations
[1]Gapparov A M, et al. Alkaloids of Convolvulus subhirsutus from Uzbekistan[J]. Chemistry of Natural Compounds, 2007, 43: 291-292.|[2]Crouzier L, et al. Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma‐1 receptor‐positive modulator with cognitive and neuroprotective properties[J]. Phytotherapy Research, 2024, 38 (2) : 694-712.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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