Syringolin A

CAT: 0804-HY-N15314Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N15314Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Syringolin A is a plant elicitor that can be produced by the plant pathogen Pseudomonas syringae pv. syringae. Syringolin A exhibits anti-proliferative activity against a variety of cancer cells (IC50 for SK-N-SH, LAN-1, SKOV3 is 20-25 µM), induces apoptosis in SK-N-SH through upregulation of p53 expression and downregulation of Akt/PKB proteins[1].
CAS Number
[212115-96-3]
UNSPSC
12352211
Target
Akt; Apoptosis; MDM-2/p53
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
CC(C)[C@@H](C(O)=O)NC(N[C@H](C(N[C@@H]1C(N[C@@H](C(C)C)/C=C/C(NCC/C=C/1)=O)=O)=O)C(C)C)=O
Molecular Formula
C24H39N5O6
Molecular Weight
493.60
References & Citations
[1]Coleman CS, et al., Syringolin A, a new plant elicitor from the phytopathogenic bacterium Pseudomonas syringae pv. syringae, inhibits the proliferation of neuroblastoma and ovarian cancer cells and induces apoptosis. Cell Prolif. 2006 Dec;39 (6) :599-609.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N8920-01Syringetin
HY-N0824-01Syringin
HY-N0824R-01Syringin (Standard)
HY-N1188Syringin pentaacetate
HY-N7889-01Syringetin-3-O-rutinoside
HY-N8194-01Syringetin-3-O-glucoside
HY-N9039Syringetin 3-O-galactoside

Alternative Products

CatalogName
MBS5790836Syringolin A
T125253-01Syringolin C
MBS5790737Syringolin B

Popular Products