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Xanthofulvin

CAT: 0804-HY-N14827Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14827Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Xanthofulvin is a semaphorin inhibitor with an IC50 of 0.09 μg/mL[1].
CAS Number
151466-15-8
Product Name Alternative
SM-216289
UNSPSC
12352211
Target
Others
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(C(C(O)=C(C=C1OC2=C3C=C(C(C)=C2C(C)=O)/C(O)=C4C(C5=C(C(O)=O)C(O)=C(O)C=C5OC/4)=O)O)=C1C3=O)O
Molecular Formula
C28H18O14
Molecular Weight
578.43
References & Citations
[1]Kazuo Kumagai, et al. Xanthofulvin, a novel semaphorin inhibitor produced by a strain of Penicillium. J Antibiot (Tokyo) . 2003 Jul;56 (7) :610-6.|[2]Maione F, Molla F, Meda C, et al. Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J Clin Invest. 2009;119 (11) :3356-3372. |[3]Kikuchi K, Kishino A, Konishi O, et al. In vitro and in vivo characterization of a novel semaphorin 3A inhibitor, SM-216289 or xanthofulvin. J Biol Chem. 2003;278 (44) :42985-42991.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
TN10805-01Xanthofulvin

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