2-Hydroxyaclacinomycin A

• Description :

  2-Hydroxyaclacinomycin A is an anthracycline antibiotic. 2-Hydroxyaclacinomycin A has the activity of inhibiting leukemia L-1210 cells, and the IC50 for RNA and DNA synthesis is 0.10 μg/mL and 0.95 μg/mL, respectively[1].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; DNA/RNA Synthesis

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage

• Field of Research :

  Cancer; Infection

• Smiles :

  O=C1C2=C(C(O)=CC(O)=C2)C(C3=C1C=C(C4=C3O)[C@@H](C(OC)=O)[C@@](O)(CC)C[C@@H]4O[C@@H]5O[C@H]([C@H]([C@H](C5)N(C)C)O[C@@H]6O[C@H]([C@H]([C@H](C6)O)O[C@@H]7O[C@H](C(CC7)=O)C)C)C)=O

• Molecular Formula :

  C42H53NO16

• Molecular Weight :

  827.87

• References & Citations :

  [1]Y Matsuzawa, et al. Reduction and hydrolysis of 2-hydroxyaclacinomycin A. J Antibiot (Tokyo) . 1981 Nov;34 (11) :1495-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [79127-36-9]