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Dihydrohonokiol B

CAT: 0804-HY-N13742-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N13742-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease[1][2].
CAS Number
219565-74-9
Product Name Alternative
Dihydrohonokiol
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Purity
99.29
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCC)C=C1C2=CC(CC=C)=C(O)C=C2
Molecular Formula
C18H20O2
Molecular Weight
268.35
References & Citations
[1]Esumi T, et al. Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan. Bioorg Med Chem Lett. 2004 May 17;14 (10) :2621-5.|[2]Liu B, et al. Anxiolytic agent, dihydrohonokiol-B, recovers amyloid beta protein-induced neurotoxicity in cultured rat hippocampal neurons. Neurosci Lett. 2005 Aug 12-19;384 (1-2) :44-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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