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Neosartoricin

CAT: 0804-HY-N12106Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N12106Size:1 Each
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Description
Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence[1][2].
CAS Number
1421941-29-8
Product Name Alternative
Fumicycline
UNSPSC
12352005
Target
Endogenous Metabolite; Fungal
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
OC1=C2C(C[C@](O)([C@@H](C2=O)OC(C)=O)CC(/C=C(O)/C)=O)=C(C3=CC(O)=CC(O)=C31)C/C=C(C)\C
Molecular Formula
C26H28O9
Molecular Weight
484.50
References & Citations
[1]Seo HW, et al. A Timeline of Biosynthetic Gene Cluster Discovery in Aspergillus fumigatus: From Characterization to Future Perspectives. J Fungi (Basel) . 2024 Apr 2;10 (4) :266.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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