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Manninotriose (Standard)

CAT: 0804-HY-N0913RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N0913RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride) . This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively) . In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
CAS Number
13382-86-0
UNSPSC
12352005
Target
Endogenous Metabolite; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
O[C@@H]([C@@H](O)[C@H](O)[C@@H](O)C=O)CO[C@H]([C@@H]([C@@H](O)[C@H]1O)O)O[C@@H]1CO[C@H]([C@@H]([C@@H](O)[C@H]2O)O)O[C@@H]2CO
Molecular Formula
C18H32O16
Molecular Weight
504.44
References & Citations
[1]dos Santos R, et al. Manninotriose is a major carbohydrate in red deadnettle (Lamium purpureum, Lamiaceae) . Ann Bot. 2013 Mar;111 (3) :385-93.|[2]Hsiao YL, et al. Treatment of acute lymphoblastic leukemia from traditional chinese medicine. Evid Based Complement Alternat Med. 2014;2014:601064.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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